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Articles (37)
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The structural elucidation of polyene macrolide antibiotics by mass spectrometry. Nystatin, amphotericin B and pimaricin

Klaus D. Haegele, Dominic M. Desiderio Jr

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1974

Langue:

english

Fichier:

PDF, 645 KB

english, 1974

Validation of a gas chromatographic/mass spectrometric method for the determination of (E)-β-fluoromethylene-m-tyrosine and its active metabolite in human plasma and urine

Josiane Schoun, Bertrand Duléry, Klaus D. Haegele

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Année:

1992

Langue:

english

Fichier:

PDF, 461 KB

english, 1992

In vitro metabolism of [14C]4-chlorobiphenyl and [14C]2,2',5,5'-tetrachlorobiphenyl by hepatic microsomes from rats and pigeons. Evidence against an obligatory arene oxide in aromatic hydroxylation reactions

Jürgen T. Borlakoglu, Klaus D. Haegele, Hans J. Reich, Raymond R. Dils, John P.G. Wilkins

Journal:

International Journal of Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1991

Assessment of the biotransformation of the cardiotonic agent piroximone by high-performance liquid chromatography and gas chromatography-mass spectrometry

Martine Berg-Candolfi, Jürgen T. Borlakoglu, Bertrand Dulery, François Jehl, Klaus D. Haegele

Journal:

Journal of Chromatography A

Année:

1992

Langue:

english

Fichier:

PDF, 541 KB

english, 1992

Determination of an irreversible inhibitor of monoamine oxidase B (MDL 72974A) in human plasma and urine by gas chromatography—positive-ion chemical ionization mass spectrometry

Bertrand D. Dulery, Josiane Schoun, Klaus D. Haegele

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1991

Langue:

english

Fichier:

PDF, 357 KB

english, 1991

Analysis of (R)-4-oxo-5-phosphononorvaline (MDL 100,453) in rat plasma and brain dialysate using liquid chromatography after derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate

Kenneth E. Cornelius, Gina M. Fadayel, Bruce M. Baron, Christopher J. Schmidt, Klaus D. Haegele, Teng-Man Chen

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

1995

Langue:

english

Fichier:

PDF, 540 KB

english, 1995

Effects of single doses of vigabatrin on CSF concentrations of GABA, homocarnosine, homovanillic acid and 5-hydroxyindoleacetic acid in patients with complex partial epilepsy

Elinor Ben Menachem, Lennart I. Persson, Paul J. Schechter, Klaus D. Haegele, Norman Huebert, Jeff Hardenberg, Lena Dahlgren, John P. Mumford

Journal:

Epilepsy Research

Année:

1988

Langue:

english

Fichier:

PDF, 615 KB

english, 1988

Determination of hydralazine and its metabolites by gas chromatography-mass spectrometry

Klaus D. Haegele, Harold B. Skrdlant, Norman W. Robie, David Lalka, John L. McNay Jr.

Journal:

Journal of Chromatography A

Année:

1976

Langue:

english

Fichier:

PDF, 1001 KB

english, 1976

Determination of the R(−)- and S(+)-enantiomers of γ-vinyl-γ-aminobutyric acid in human body fluids by gas chromatography—mass spectrometry

Klaus D. Haegele, Josiane Schoun, Rudolph G. Alken, Norman D. Huebert

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1983

Langue:

english

Fichier:

PDF, 507 KB

english, 1983

Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis

Michael A. Cornbleet, Andrew Kingsnorth, Guy P. Tell, Klaus D. Haegele, Anne-Marie Joder-Ohlenbusch, John F. Smyth

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 437 KB

english, 1989

A single-dose-finding study of the antiemetic effect and associated plasma levels of MDL 72222 in patients receiving cisplatin

John Logue, Peter Wilkinson, Klaus D. Haegele, John Orwin

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 578 KB

english, 1991

Quantitative analysis of hydralazine pyruvic acid hydrazone, the major plasma metabolite of hydralazine

Klaus D. Haegele, Harold B. Skrdlant, Tore Talseth, John L. McNay, Alexander M.M. Shepherd, William A. Clementi

Journal:

Journal of Chromatography A

Année:

1980

Langue:

english

Fichier:

PDF, 641 KB

english, 1980

Kinetics of α-difluoromethylornithine: An irreversible inhibitor of ornithine decarboxylase

Haegele, Klaus D, Alken, Rudolf G, Grove, Jeffrey, Schechter, Paul J, Koch-Weser, Jan

Journal:

Clinical Pharmacology & Therapeutics

Année:

1981

Langue:

english

Fichier:

PDF, 428 KB

english, 1981

Kinetics of fenoximone, a new cardiotonic, in healthy subjects

Alken, Rudolf G, Belz, Gustav G, Haegele, Klaus D, Meinicke, Thomas, Schechter, Paul J

Journal:

Clinical Pharmacology & Therapeutics

Année:

1984

Langue:

english

Fichier:

PDF, 421 KB

english, 1984

Kinetics of the enantiomers of vigabatrin after an oral dose of the racemate or the active S-enantiomer

Haegele, Klaus D, Schechter, Paul J

Journal:

Clinical Pharmacology & Therapeutics

Année:

1986

Langue:

english

Fichier:

PDF, 284 KB

english, 1986

Pharmacokinetics of vigabatrin: Implications of creatinine clearance

Haegele, Klaus D, Huebert, Norman D, Ebel, Marc, Tell, Guy P, Schechter, Paul J

Journal:

Clinical Pharmacology & Therapeutics

Année:

1988

Langue:

english

Fichier:

PDF, 469 KB

english, 1988

Evidence for a Novel Pentyl Radical Adduct of the Cyclic Nitrone Spin Trap MDL 101,002

Jeffrey L Dage, Bradley L Ackermann, Robert J Barbuch, Ronald C Bernotas, David F Ohlweiler, Klaus D Haegele, Craig E Thomas

Journal:

Free Radical Biology and Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 191 KB

english, 1997

Absorption of angiotensin II antagonists in Ussing chambers, Caco-2, perfused jejunum loop and in vivo:: Importance of drug ionisation in the in vitro prediction of in vivo absorption

Michel Boisset, Roger P. Botham, Klaus D. Haegele, Bernard Lenfant, Jean I. Pachot

Journal:

European Journal of Pharmaceutical Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 186 KB

english, 2000

Difluoromethylornithine, an effective new treatment of gambian trypanosomiasis: Results in five patients

Henri Taelman, Paul J. Schechter, Luc Marcelis, Jean Sonnet, Gaston Kazyumba, Jean Dasnoy, Klaus D. Haegele, Albert Sjoerdsma, Marc Wery

Journal:

The American Journal of Medicine

Année:

1987

Langue:

english

Fichier:

PDF, 898 KB

english, 1987

pNAT and CYP2D6 gene polymorphism in epileptic patients

Jürgen T. Borlak, Veronique Harsany, Hansjörg Schneble, Klaus D. Haegele

Journal:

Biochemical Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 410 KB

english, 1994

Frontolimbic brain abnormalities in patients with borderline personality disorder: a volumetric magnetic resonance imaging study

Ludger Tebartz van Elst, Bernd Hesslinger, Thorsten Thiel, Emanuel Geiger, Kerstin Haegele, Louis Lemieux, Klaus Lieb, Martin Bohus, Jürgen Hennig, Dieter Ebert

Journal:

Biological Psychiatry

Année:

2003

Langue:

english

Fichier:

PDF, 178 KB

english, 2003

Electrophysiological effects of intravenous MDL 17.043

Pop, Tiberius, Treese, Norbert, Cremer, Gabrielle M.J., Haegele, Klaus D., Meyer, Jürgen

Journal:

International Journal of Cardiology

Année:

1986

Langue:

english

Fichier:

PDF, 640 KB

english, 1986

A cardioselective, hydrophilic N,N,N-trimethylethanaminium .alpha.-tocopherol analog that reduces myocardial infarct size

Grisar, J. Martin, Petty, Margaret A., Bolkenius, Frank N., Dow, James, Wagner, Joseph, Wagner, Eugene R., Haegele, Klaus D., De Jong, Wybren

Journal:

Journal of Medicinal Chemistry

Année:

1991

Langue:

english

Fichier:

PDF, 583 KB

english, 1991

Occurrence of gas phase ammonolysis during chemical ionization mass spectrometry

Haegele, Klaus D., Desiderio, Dominic M.

Journal:

Journal of Organic Chemistry

Année:

1974

Langue:

english

Fichier:

PDF, 432 KB

english, 1974

Melcanthin A, B, and C, three new cis-1(10),cis-4,5-germacranolides from Melampodium leucanthum (Compositae, Helianthae)

Fischer, Nikolaus H., Seaman, Fred C., Wiley, Russell A., Haegele, Klaus D.

Journal:

Journal of Organic Chemistry

Année:

1978

Langue:

english

Fichier:

PDF, 529 KB

english, 1978

Photodynamic and Radiolytic Inactivation of Ion Channels Formed by Gramicidin A: Oxidation and Fragmentation

Kunz, Lars, Zeidler, Ulrich, Haegele, Klaus, Przybylski, Michael, Stark, Guenther

Journal:

Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1995

Comment on the Cylindrical Capacitor Electrospray Interface

König, Simone, Fales, Henry M., Haegele, Klaus D.

Journal:

Analytical Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 63 KB

english, 1998

Melampodinin, leucanthinin, and melampolidin, three new melampolides from Melampodium (Compositae)

Fischer, Nikolaus H., Wiley, Russell A., Perry, Donald L., Haegele, Klaus D.

Journal:

Journal of Organic Chemistry

Année:

1976

Langue:

english

Fichier:

PDF, 585 KB

english, 1976

Structure revision of the antibiotic pulvomycin

Smith, Richard J., Williams, Dudley H., Barna, Jennifer C. J., McDermott, Ian R., Haegele, Klaus, Piriou, Francois, Wagner, Joseph, Higgins, William

Journal:

Journal of the American Chemical Society

Année:

1985

Langue:

english

Fichier:

PDF, 1.59 MB

english, 1985

Determination of phenylethylmalonamide by electron-capture gas chromatography

Wallace, Jack E., Hamilton, Horace E., Shimek, Eugene L., Schwertner, Harvey A., Haegele, Klaus D.

Journal:

Analytical Chemistry

Année:

1977

Langue:

english

Fichier:

PDF, 595 KB

english, 1977

Kinetics of medroxalol, a β- and α-adrenoceptor antagonist

Haegele, Klaus D, Jaillon, Patrice, Cheymol, Georges, Alken, Rudolf G, Schechter, Paul J, Koch-Weser, Jan

Journal:

Clinical Pharmacology & Therapeutics

Année:

1983

Langue:

english

Fichier:

PDF, 413 KB

english, 1983

Hypertensive Effect of the Hydralazine—Acetone Hydrazone in Conscious Rabbits

Talseth, Tore, McNay, John L., Haegele, Klaus D.

Journal:

Journal of Cardiovascular Pharmacology

Année:

1982

Fichier:

PDF, 308 KB

1982

β and α-Adrenoceptor Antagonism by Medroxalol in Healthy Volunteers

Jaillon, Patrice, Weissenburger, Jacques, Biour, Michel, Cheymol, Georges, Haegele, Klaus, Schechter, Paul J., Koch-Weser, jan

Journal:

Journal of Cardiovascular Pharmacology

Année:

1982

Fichier:

PDF, 583 KB

1982

Hemodynamic Effects of MDL 17,043, a New Cardiotonic Agent, in Patients with Congestive Heart Failure

Arbogast, Robert, Brandt, Christian, Haegele, Klaus D., Fincker, Jean Louis, Schechter, Paul J.

Journal:

Journal of Cardiovascular Pharmacology

Année:

1983

Fichier:

PDF, 453 KB

1983

STRUCTURAL ELUCIDATION OF MINOR COMPONENTS IN THE ANTIMYCIN A COMPLEX BY MASS SPECTROMETRY

HAEGELE, KLAUS D., DESIDERIO, D. M.

Journal:

The Journal of Antibiotics

Année:

1973

Langue:

english

Fichier:

PDF, 437 KB

english, 1973

Kinetics and metabolism of p-tyramine during monoamine oxidase inhibition by mofegiline

Huebert, Norman D, Dulery, Bertrand D, Schoun, Josiane, Schwach, Valérie, Hinze, Christian, Haegele, Klaus D

Journal:

Clinical Pharmacology & Therapeutics

Année:

1994

Langue:

english

Fichier:

PDF, 501 KB

english, 1994

ChemInform Abstract: SILICON-MATRIZEN FUER DIE FESTPHASEN-PEPTIDSYNTHESE

PARR, WOLFGANG, GROHMANN, KARL, HAEGELE, KLAUS

Journal:

Chemischer Informationsdienst

Année:

1974

Fichier:

PDF, 119 KB

1974